Wag the Dog

On Simulacra in Wag the Dog

Myosin structure: Does the tail wag the dog?

Previous crystal structures of the myosin head have shown two different conformations, postulated to be the beginning and the end of the actomyosin power stroke. A new crystal structure reveals a dramatically different conformation; but how does this conformation fit into the force-generating cycle of actomyosin interactions?

Wag the dog: skepticism on seizure alert canines.

Some dogs can signal human seizure activity. Seizure response dogs (SRDs) recognize and respond to ongoing seizure and postseizure compromise, whereas seizure alert dogs (SADs) may warn of impending seizure.1-5 Canine companions may have an additional stress reduction benefit that can lead to decreased seizure frequency.5 In this report we describe a dog that warns of psychogenic nonepileptifor...

Does the Dog Wag the Tail or the Tail the Dog? Cointegration of Indian Agriculture with Nonagriculture

An oft-repeated refrain in the development literature has been the “neglect” of the agricultural sector vis-à-vis the industrial sector in the development process of the less developed economies. Because infrastructure is crucially linked to both agricultural and industrial development, poor infrastructure development may make it appear as if slow agricultural growth has caused slow industrial ...

When the tail can't wag the dog: the implications of CNS-intrinsic initiation of neuroinflammation

The CNS (central nervous system) is unquestionably the central organ that regulates directly or indirectly all physiological systems in the mammalian body. Yet, when considering the defence of the CNS from pathogens, the CNS has often been considered passive and subservient to the pro-inflammatory responses of the immune system. In this view, neuroinflammatory disorders are examples of when the...